Bioequivalence and Bioavailability Forum • F value for sequence effect

F value for sequence effect [🇷 for BE/BA]

posted by Pakawadee – 2010-05-03 13:48 (5481 d 17:50 ago) – Posting: # 5273
Views: 26,204

Response: lnCmax

          Df   Sum Sq  Mean Sq F value Pr(>F)

seq        1 0.000017 0.000017  0.0011 0.9743

prd        1 0.027294 0.027294  1.7187 0.2144

drug       1 0.025583 0.025583  1.6110 0.2284

seq:subj  12 0.255270 0.021273  1.3395 0.3103

Residuals 12 0.190565 0.015880

The above ANOVA table is an example in this webpage. I am confused about F value of sequence. Why it is 0.0011 (=MSseq/MSresidual)? I think it should be 0.0008 (=MSseq/MSsubj). Due to my knowledge in statistic is very limit, I afraid that I would missunderstand some concept of ANOVA for BE. May anyone help to explain?
Thanks
Pakawadee

Edit: Not in this webpage, but in the example (second output) of bear's homepage. BTW, testing for a sequence effect (or unequal carry-over, if you like) in 2×2 cross-over studies is futile anyhow (see this post). [Helmut]

Complete thread:

F value for sequence effectPakawadee 2010-05-03 11:48 [🇷 for BE/BA]
- F value for sequence effect AA 2010-05-03 13:38
- F value for sequence effect Ohlbe 2010-05-03 14:16
  - F value for sequence effect Pakawadee 2010-05-04 03:48
    - F value for sequence effect ElMaestro 2010-05-04 08:48
      - F value for sequence effect Pakawadee 2010-05-04 12:12
      - F value; rounding Helmut 2010-05-04 13:00
        
        log rounding machine d_labes 2010-05-04 13:35
        Rounding or not to rounding yjlee168 2010-05-04 21:27
        
        Rounding or not to rounding ElMaestro 2010-05-04 23:23
        
        Rounding or not to rounding yjlee168 2010-05-05 01:17
        
        Rounding or not to rounding ElMaestro 2010-05-05 12:15
        
        Rounding or not to rounding yjlee168 2010-05-05 12:59
        
        Rounding or not to rounding ElMaestro 2010-05-05 13:15
        
        Rounding or not to rounding yjlee168 2010-05-05 13:28
        Type III SS sequence effect -revised yjlee168 2010-05-05 23:58
        
        Type III SS sequence effect -revised ElMaestro 2010-05-06 07:27
        
        SAS-like Type III SS sequence with bear? yjlee168 2010-06-03 13:04
        
        New dataset? d_labes 2010-05-05 11:40
        
        New dataset? yjlee168 2010-05-05 12:31
        
        log to 3 decimals guess work d_labes 2010-05-05 16:00
        
        log to 3 decimals guess work yjlee168 2010-05-05 20:13
        
        rounding and presentation of data Helmut 2010-05-05 20:29
        
        rounding and presentation of data yjlee168 2010-05-05 21:05
        
        rounding and presentation of data in R martin 2010-05-06 07:53
        
        Canadian logs d_labes 2010-05-06 10:12
        
        Canadian logs ElMaestro 2010-05-06 10:21
        Canadian logs Helmut 2010-05-06 14:57
        
        Canadian lost d_labes 2010-05-06 15:38