Bioequivalence and Bioavailability Forum

Hello everyone,

I have one question.

We have profiles from 1000 mg single dose of a drug and want to predict 500mg profiles of the same drug given as Bid. at an interval of 12 hrs using data from 1000mg single dose profile.

Now my question is Can we predict 500 mg bid. profile using non parametric superposition option of the winNonlin 5.2 version. If yes Please tell the procedure and if No please mention the software on which this can be done.

Thanks in advance.

Regards,
Ravi Pandey

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Edit: Category changed. [Helmut]