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RegisterPre-clinical PK/PD Parameters [PK / PD]
Hello all,
When i was going through the PK parameters of an antibacterial drug, i got stuck up at one point with the background concept behind.
So basically, the three parameters are, Concentration/MIC, Time>MIC, AUC/MIC - These are the Gold standard for evaluating Antibiotic PK-PD & Dosage regimen.
My question is,
1. How the drugs(Antibiotics) are classified under one of these parameters ?
E.g - Aminoglycoside - it comes under Concentration dependent killing (i.e, Conc/MIC).
why can't this come under time/MIC ??
Please kindly help me out.
Thanks in Advance !!
When i was going through the PK parameters of an antibacterial drug, i got stuck up at one point with the background concept behind.
So basically, the three parameters are, Concentration/MIC, Time>MIC, AUC/MIC - These are the Gold standard for evaluating Antibiotic PK-PD & Dosage regimen.
My question is,
1. How the drugs(Antibiotics) are classified under one of these parameters ?
E.g - Aminoglycoside - it comes under Concentration dependent killing (i.e, Conc/MIC).
why can't this come under time/MIC ??
Please kindly help me out.
Thanks in Advance !!
—
With Best Regards,
Vroy.
With Best Regards,
Vroy.
Complete thread:
- Pre-clinical PK/PD ParametersVijithRoy 2020-07-22 07:34 [PK / PD]
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Pre-clinical PK/PD Parameters dshah 2020-07-30 13:09
- MIC: in vitro… Helmut 2020-07-30 13:41
- Pre-clinical PK/PD Parameters VijithRoy 2020-07-31 08:18
- Pre-clinical PK/PD Parameters dshah 2020-07-30 13:09
Ing. Helmut Schütz