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RegisterFour period study with four treatment [Design Issues]
Dear HS,
Can we plan a four period crossover BE Study with four treatments R1, R2 and T1, T2 comparing R1 with T1 and R2 with T2 separately.
Randomisation sequence would be defined as follows
Kindly let me is it correct to conclude Bioequivalence by comparing R1 with T1 and R2 with T2 as if there were two periods.
Regards,
Atish
Can we plan a four period crossover BE Study with four treatments R1, R2 and T1, T2 comparing R1 with T1 and R2 with T2 separately.
Randomisation sequence would be defined as follows
+-----+----+----+----+----+
| S/P | 1 | 2 | 3 | 4 |
+-----+----+----+----+----+
| A | R1 | T1 | R2 | T2 |
| B | T1 | R1 | T2 | R2 |
|-----+----+----+----+----+Kindly let me is it correct to conclude Bioequivalence by comparing R1 with T1 and R2 with T2 as if there were two periods.
Regards,
Atish
Complete thread:
- Four period study with four treatmentatish_azad 2008-07-18 18:37 [Design Issues]
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Four period study with four treatment Helmut 2008-07-18 22:22
- Four period study with four treatment vijay 2008-07-20 21:26
- Randomization; Balanced Incomplete Block Design Helmut 2008-07-21 20:39
- Randomization; Balanced Incomplete Block Design atish_azad 2008-07-25 18:34
- Randomization; Balanced Incomplete Block Design Helmut 2008-07-21 20:39
- Four period study with four treatment vijay 2008-07-20 21:26
- Four period study with four treatment Helmut 2008-07-18 22:22
Ing. Helmut Schütz