Bioequivalence and Bioavailability Forum • Any post about difference between 4x4 and 4x2 in bioequivalence studies?

Any post about difference between 4x4 and 4x2 in bioequivalence studies? [Design Issues]

posted by Mauricio Sampaio – Brazil, 2016-11-03 19:54 (3521 d 23:08 ago) – Posting: # 16769
Views: 8,314

I am looking for a post in this forum that explain what is the best design to replicate a bioequivalence study. The 4x4 or 4x2? Normally, I use 4x4 this is a best choice? Or I can use 4x2 with same eficcacy?

Complete thread:

Any post about difference between 4x4 and 4x2 in bioequivalence studies?Mauricio Sampaio 2016-11-03 18:54 [Design Issues]
- Not more than 2 sequences in full replicates Helmut 2016-11-03 19:38
  - Not more than 2 sequences in full replicates Astea 2016-11-04 08:22
    - Only RR is used Helmut 2016-11-11 20:52
  - Not more than 2 sequences in full replicates Mauricio Sampaio 2016-11-11 18:39