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RegisterStatistical Comparison Tmax [Nonparametrics]
Phoenix WinNonlin 6.4 provides a routine for statistical comparison of Tmax from a 2 way crossover study (Latin Square, 2 periods, 2 sequences) as a non-parametric parameter and confidence intervals are provided. I do not see intrasubject and intersubject variances in the output and I have just made a post to the Pharsight site regarding this.
For bioequivalence of Cmax and AUC pamameters intrasubject and intersubject variance is provided. So I am thinking how to obtain analogous information on Tmax parameter for a two-way cross-over study. I wonder if anyone has done this.
Angus
Edit: Category changed. [Helmut]
For bioequivalence of Cmax and AUC pamameters intrasubject and intersubject variance is provided. So I am thinking how to obtain analogous information on Tmax parameter for a two-way cross-over study. I wonder if anyone has done this.
Angus
Edit: Category changed. [Helmut]
Complete thread:
- Statistical Comparison TmaxAngusMcLean 2015-05-16 17:11 [Nonparametrics]
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- no parameters in nonparametric tests… Helmut 2015-05-16 18:50
- no parameters in nonparametric tests… AngusMcLean 2015-05-16 19:57
- no parameters in nonparametric tests… Helmut 2015-05-17 00:33
- no parameters in nonparametric tests… AngusMcLean 2015-05-16 19:57
- no parameters in nonparametric tests… Helmut 2015-05-16 18:50
Ing. Helmut Schütz