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RegisterInterference Peak [Bioanalytics]
Dear Group Members,
During subject plasma sample analysis by LC/MS/MS, an extra peak (possibly due to metabolite) is observed which is not completely separated from the drug peak. But Method Validation was performed without the metabolite (as per OGD communication) & there was no interference peak during method validation. In such a situation, how should the analyst proceed with subject sample analysis?
Thanks & regards,
Dr. Harish L. Rao
During subject plasma sample analysis by LC/MS/MS, an extra peak (possibly due to metabolite) is observed which is not completely separated from the drug peak. But Method Validation was performed without the metabolite (as per OGD communication) & there was no interference peak during method validation. In such a situation, how should the analyst proceed with subject sample analysis?
Thanks & regards,
Dr. Harish L. Rao
Complete thread:
- Interference PeakDr. Harish L. Rao 2007-09-20 09:42 [Bioanalytics]
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Resolution >2! Helmut 2007-09-20 12:56
- Resolution >2! Ohlbe 2007-09-21 01:55
- Interference Peak vamshi 2008-08-14 12:49
- Resolution >2! Helmut 2007-09-20 12:56
Ing. Helmut Schütz