Bioequivalence and Bioavailability Forum • Internal Standard Variation

Internal Standard Variation [Bioanalytics]

posted by Dr. Harish L. Rao – India, 2007-09-08 16:16 (6474 d 20:27 ago) – Posting: # 1060
Views: 17,574
(edited on 2007-09-09 12:48)

Dear Group Members,

How much of Internal Standard (ISTD) Peak Area Variation is allowed for bioanalysis during Method Validation & Study Sample Analysis by HPLC and LC-MS/MS? Is there any guideline for this?

Thanks & regards,
Dr. Harish L. Rao

Complete thread:

Internal Standard VariationDr. Harish L. Rao 2007-09-08 14:16 [Bioanalytics]
- Internal Standard Variation Helmut 2007-09-08 16:43
  - Internal Standard Variation Ohlbe 2007-09-08 22:32
    - Internal Standard Variation Helmut 2007-09-09 00:37
      - Internal Standard Variation Charl 2007-09-09 12:25
        
        Internal Standard Variation Jaime_R 2007-09-09 13:13
        
        IS vs ES methods Helmut 2007-09-09 15:05
        Internal Standard Variation Charl 2007-09-10 10:10
        
        Internal Standard Variation Jaime_R 2007-09-10 18:58
      - Internal Standard Variation Ohlbe 2007-09-09 23:20
        
        Internal Standard Variation Helmut 2007-09-10 20:33
- Internal Standard Variation vamshi 2008-08-14 12:33
  - Internal Standard Variation ElMaestro 2008-08-14 14:09
    - Internal Standard Variation Helmut 2008-08-14 20:28
      - Internal Standard Variation ElMaestro 2008-08-15 16:51
        
        Internal Standard Variation Helmut 2008-08-15 17:29