Bioequivalence and Bioavailability Forum • Calibration Curve

Calibration Curve [Bioanalytics]

posted by auditor – India, 2012-01-20 12:15 (5266 d 22:16 ago) – Posting: # 7973
Views: 6,799

Hi,
We would like to know how to plot calibration curve if there are duplicate standards used at LLOQ & ULOQ levels?
For example: if we take 8 standards (each of diferent level) for plotting a curve, wherein 2 levels are in duplicate (LLOQ & ULOQ) i.e. total 10 no of samples (standards). In such case if all the standards are paasing the criteria including both the duplicates then all 10 standard needs to be considered or mean of duplicates (LLOQ & ULOQ) needs to be considered while plotting the curve?

Regards,
Auditor

Complete thread:

Calibration Curveauditor 2012-01-20 11:15
- Duplicate LLOQ and ULOQ Ohlbe 2012-01-20 11:59
  - Duplicate LLOQ and ULOQ Helmut 2012-01-20 13:09
    - Duplicate LLOQ and ULOQ Ohlbe 2012-01-20 14:26
      - Duplicate LLOQ and ULOQ Helmut 2012-01-20 18:02
        
        Calibration Curve auditor 2012-01-21 05:45
        
        Calibration Curve Helmut 2012-01-21 12:35
        Calibration Curve Ohlbe 2012-01-21 13:44
        
        Calibration Curve Helmut 2012-01-22 21:48