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RegisterCross-validation? [Bioanalytics]
Dear all,
I would agree with Debbie, at least if you have demonstrated that you have no selectivity issue and no ion suppression / enhancement from any of the 3 metabolites and corresponding 3 SIL IS on the parent and corresponding IS.
(If you did have selectivity or matrix effects issues, your combined method would be flawed anyway as you will never have a fixed proportion of the 4 analytes in your study samples).
Regards
Ohlbe
I would agree with Debbie, at least if you have demonstrated that you have no selectivity issue and no ion suppression / enhancement from any of the 3 metabolites and corresponding 3 SIL IS on the parent and corresponding IS.
(If you did have selectivity or matrix effects issues, your combined method would be flawed anyway as you will never have a fixed proportion of the 4 analytes in your study samples).
Regards
Ohlbe
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Regards
Ohlbe
Regards
Ohlbe
Complete thread:
- Cross-validation? moblak 2010-04-21 16:06
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Cross-validation? Geokad 2010-04-23 17:50
- Cross-validation? moblak 2010-04-28 11:49
- Cross-validation? Debbie 2010-04-28 17:53
- Cross-validation?Ohlbe 2010-04-29 00:38
- Cross-validation? Debbie 2010-04-28 17:53
- Cross-validation? moblak 2010-04-28 11:49
- Cross-validation? Geokad 2010-04-23 17:50
Ing. Helmut Schütz