Bioequivalence and Bioavailability Forum

An old solution [Bioanalytics]

posted by Helmut  – Vienna, Austria, 2019-03-17 00:05 (2260 d 23:39 ago) – Posting: # 20042
Views: 7,118

Hi ElMaestro,

❝ […] The smartest and most empirical solution to a very, very small (and mainly theoretical?) problem.

Theoretical? Yes. Really relevant? Very, very rarely. Changing the weighting for all subjects to 1/y² (we got two deficiency letters) altered the 90% CI in the second decimal place.

❝ Let us apply weights 1/C^z in such a fashion that ()

Congratulations for an obvious solution (aka, re-inventing the wheel). See what Ohlbe wrote here and there.

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PS: Typo? Didn’t you want Ratio[1]=0.05303?

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна! 
Helmut Schütz


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Complete thread:

• Handling BLOQ values (Fisher Info etc.) mittyri 2019-03-16 14:41 
  • Handling BLOQ values (Fisher Info etc.) Helmut 2019-03-16 15:39
    • The smartest solution ElMaestro 2019-03-16 22:35
      • An old solutionHelmut 2019-03-16 23:05
        • old, obvious? ElMaestro 2019-03-19 08:26
      • Example Helmut 2019-03-17 01:56
    • ADA example mittyri 2019-03-18 22:20
      • My beloved Ada Helmut 2019-03-19 01:34
  • Handling BLOQ values (Fisher Info etc.) Ohlbe 2019-03-17 14:32
    • Handling BLOQ values (Fisher Info etc.) nobody 2019-03-18 08:14
      • Don’t weight by 1/s² Helmut 2019-03-18 11:19