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RegisterPurpose of S:N? [Bioanalytics]
posted by Helmut 
– Vienna, Austria, 2018-11-09 12:26 (2780 d 19:46 ago) – Posting: # 19553
Views: 14,573
Hi ElMaestro,
Oh dear, I missed that for years. Biased perception.
Let me continue my series of methods. Number 3: A/P 10/10% but S:N 3:1. Although I have some doubts whether we can achieve such a nice A/P with such a bad S:N, let it be. I consider this one the "best" of the three. I would never ever use one of the others only cause the S:N is higher.
❝ EMA: " (...) the analyte signal of the LLOQ sample should be at least 5 times the signal of a blank sample"
Oh dear, I missed that for years. Biased perception.
❝ So, it becomes a choice between doing something meaningful or doing something that appears compliant with the guideline 
Let me continue my series of methods. Number 3: A/P 10/10% but S:N 3:1. Although I have some doubts whether we can achieve such a nice A/P with such a bad S:N, let it be. I consider this one the "best" of the three. I would never ever use one of the others only cause the S:N is higher.
—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png)
Helmut Schütz
![[image]](https://static.bebac.at/img/CC by.png)
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Isn't it time for an open source chromatographic format ElMaestro 2018-11-04 21:54
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Isn't it time for an open source chromatographic format nobody 2018-11-05 09:00
- and now that we are at it ElMaestro 2018-11-05 13:53
- and now that we are at it nobody 2018-11-05 16:33
- and now that we are at it ElMaestro 2018-11-05 18:19
- Transparent ruler – like in the good ol’ days Helmut 2018-11-05 20:39
- Transparent ruler – like in the good ol’ days Ohlbe 2018-11-05 22:14
- Transparent ruler – like in the good ol’ days ElMaestro 2018-11-05 22:43
- Slow down, you move too fast […] Feelin’ Groovy Helmut 2018-11-06 02:05
- Slow down, you move too fast […] Feelin’ Groovy nobody 2018-11-06 09:29
- Yes it went a little fast ElMaestro 2018-11-06 11:09
- Yes it went a little fast nobody 2018-11-06 12:05
- Yes it went a little fast ElMaestro 2018-11-06 12:10
- Yes it went a little fast Helmut 2018-11-07 16:09
- Yes it went a little fast ElMaestro 2018-11-07 16:22
- Yes it went a little fast nobody 2018-11-07 18:30
- Purpose of S:N? Helmut 2018-11-08 09:46
- Purpose of S:N? ElMaestro 2018-11-08 22:27
- Purpose of S:N? nobody 2018-11-09 10:06
- Purpose of S:N? Helmut 2018-11-09 11:34
- Purpose of S:N? nobody 2018-11-09 12:08
- Purpose of S:N? Helmut 2018-11-09 12:34
- Purpose of S:N? nobody 2018-11-09 12:08
- Purpose of S:N? Helmut 2018-11-09 11:34
- Purpose of S:N?Helmut 2018-11-09 11:26
- Purpose of S:N? ElMaestro 2018-11-09 13:16
- Purpose of S:N? nobody 2018-11-09 10:06
- Purpose of S:N? ElMaestro 2018-11-08 22:27
- Yes it went a little fast ElMaestro 2018-11-07 16:22
- Yes it went a little fast Helmut 2018-11-07 16:09
- Yes it went a little fast ElMaestro 2018-11-06 12:10
- Yes it went a little fast nobody 2018-11-06 12:05
- Yes it went a little fast ElMaestro 2018-11-06 11:09
- Slow down, you move too fast […] Feelin’ Groovy nobody 2018-11-06 09:29
- Slow down, you move too fast […] Feelin’ Groovy Helmut 2018-11-06 02:05
- Transparent ruler – like in the good ol’ days ElMaestro 2018-11-05 22:43
- Transparent ruler – like in the good ol’ days Ohlbe 2018-11-05 22:14
- and now that we are at it nobody 2018-11-05 16:33
- and now that we are at it ElMaestro 2018-11-05 13:53
- Isn't it time for an open source chromatographic format paulhurleyuk 2018-11-05 16:27
- Isn't it time for an open source chromatographic format nobody 2018-11-05 09:00
Ing. Helmut Schütz