Bioequivalence and Bioavailability Forum • Concomitant medications experiment in method validation

Concomitant medications experiment in method validation [Bioanalytics]

posted by chandru – India, 2018-02-14 08:31 (2657 d 11:21 ago) – Posting: # 18416
Views: 6,328
(edited on 2018-02-14 10:02)

Hi all,

How to evaluate the effect of concomitant medications during validation?

We add the concomitant medications to LLOQ of analyte and compare against the calibration standard.

Any additional experiment has to be performed to evaluate its effect.

Regards,
Chandru

Complete thread:

Concomitant medications experiment in method validationchandru 2018-02-14 07:31
- Concomitant medications experiment in method validation Obinoscopy 2018-05-02 04:05
- Concomitant medications experiment in method validation ElMaestro 2018-05-02 09:25
  - Enhancement from concomitant medications Ohlbe 2018-05-02 11:36
    - Enhancement from concomitant medications ElMaestro 2018-05-02 12:23
      - Enhancement from concomitant medications Ohlbe 2018-05-02 12:34
        
        US FDA guidance chandru 2018-05-27 21:41