Bioequivalence and Bioavailability Forum

Change in curve changed the ratio of Cmax [Bioanalytics]

posted by nobody – 2015-03-23 17:11 (4115 d 06:01 ago) – Posting: # 14601
Views: 14,241

❝ ...

❝ I would like to add one thing that, i had done comparison of Cmax data between originally run assay and repeat study and found there is a difference of around 8-10% (negative side) and the same is getting reflected in the Cmax ratio.

...again: did the slope differ between method 1 and 2?

And again: Nobody (not eve the real one ) can decide the results are valid without having a deep look into your lab notebooks and reports

Complete thread:

• Change in curve changed the ratio of Cmax Compliance 2015-03-23 07:39 
  • Change in curve changed the ratio of Cmax Dr_Dan 2015-03-23 08:59
    • Change in curve changed the ratio of Cmax Compliance 2015-03-23 09:27
  • Change in curve changed the ratio of Cmax nobody 2015-03-23 09:19
    • Change in curve changed the ratio of Cmax Compliance 2015-03-23 10:09
      • Change in curve changed the ratio of Cmax nobody 2015-03-23 10:34
        • Change in curve changed the ratio of Cmax Compliance 2015-03-23 10:53
  • Change in curve changed the ratio of Cmax Ohlbe 2015-03-23 14:13
    • Change in curve changed the ratio of Cmax Compliance 2015-03-23 15:29
      • Change in curve changed the ratio of Cmaxnobody 2015-03-23 16:11
  • Change in curve changed the ratio of Cmax Dr_Dan 2015-03-24 08:15
    • Change in curve changed the ratio of Cmax Compliance 2015-03-24 09:39
  • Change in curve changed the ratio of Cmax Dr_Dan 2015-03-24 11:05
    • Change in curve changed the ratio of Cmax Compliance 2015-03-25 12:13