Bioequivalence and Bioavailability Forum • Reporting of plasma concentration data etc

Reporting of plasma concentration data etc [Bioanalytics]

posted by jag009 – NJ, 2014-09-19 17:26 (3901 d 13:30 ago) – Posting: # 13541
Views: 12,942

❝ As pointed out: You can report/calculate with 17 sig digits, however, most of it is random noise.

❝

❝ Face it: if a postive BE decision depends on stuff like that, your product is, eeehm,... imperfect ***cough***

True but we live in a world where these bloody #s mean pass or fail and you will not be surprised how many "successful" BE studies are borderline passing with low end of 90%CI like 80.1, 80.05 or high end like 124.9, 124.8...

I just don't like the inconsistency of the labs. Some go with 3 decimal places, some go with 3 significant figures.

John

Complete thread:

Reporting of plasma concentration data etc jag009 2014-09-18 21:32
- Reporting of plasma concentration data etc Ohlbe 2014-09-18 21:50
  - Reporting of plasma concentration data etc jag009 2014-09-18 22:22
    - Reporting of plasma concentration data etc Ohlbe 2014-09-19 12:26
  - Reporting of plasma concentration data etc d_labes 2014-09-19 08:46
    - Reporting of plasma concentration data etc nobody 2014-09-19 10:31
      - Reporting of plasma concentration data etcjag009 2014-09-19 15:26
        
        Reporting of plasma concentration data etc nobody 2014-09-19 16:01
        
        Reporting of plasma concentration data etc jag009 2014-09-26 16:29
- Reporting of plasma concentration data etc SDavis 2014-09-25 15:10
  - Reporting of plasma concentration data etc Helmut 2014-09-25 16:11
  - Reporting of plasma concentration data etc jag009 2014-09-26 16:22
    - Reporting of plasma concentration data etc Ohlbe 2014-09-28 13:53
  - Reporting of plasma concentration data etc ElMaestro 2014-09-28 15:07
    - SAS vs. PHX/WNL Helmut 2014-09-28 17:21
- Numbers should reflect the precision of the instrumentation Helmut 2014-09-28 19:34