Non-weighting to weighting method [Bioanalytics]

posted by Ken Peh – Malaysia, 2014-08-18 20:43 (3936 d 04:56 ago) – Posting: # 13402
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Dear Members,

Would highly appreciate your input and kind sharing for the following scenario.

Method validation has been carried out on the drug where standard calibration curve was quantified without using weighting factor. We were told (later) that weighting factor was allowed.
  1. Can we recalculate the data using weighting factor for MV and then use this weighting method in the analysis of study samples ?
  2. Do we need to qualify by running partial validation ? Why ? :confused:

We found that using weighting factor is easier to pass the standard calibration curve.

Thank you.

Regards,
Ken

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