Column-switching? [Bioanalytics]

posted by AngusMcLean – USA, 2014-06-02 22:45 (4011 d 21:12 ago) – Posting: # 13027
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Lyn: Helmut is indeed correct the above sample preparation procedure for a stable amine is not applicable to an acid labile drug like omeprazole. I think as Helmut suggest SPE may work or perhaps an extraction with a solvent of minimal polarity yet still cable of extracting the drug.

Angus

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