Recovery [Bioanalytics]
Dear Nobody,
I'd say recovery is more something to check during method development, to optimise your extraction method. But indeed it is of limited interest in method validation. That is, unless indeed the FDA requests it to be done on 6 different sources of matrix, as planned in their draft BMV guideline. I've seen a poster recently mentioning a variable recovery from one lot to the next.
❝ [...] in most cases recovery is not very interesting. More a parameter to take care for while debugging, in my opinion...
I'd say recovery is more something to check during method development, to optimise your extraction method. But indeed it is of limited interest in method validation. That is, unless indeed the FDA requests it to be done on 6 different sources of matrix, as planned in their draft BMV guideline. I've seen a poster recently mentioning a variable recovery from one lot to the next.
—
Regards
Ohlbe
Regards
Ohlbe