Bioequivalence and Bioavailability Forum

Extrapolation <LLOQ or >ULOQ [Bioanalytics]

posted by Charl – 2007-10-23 11:27 (6820 d 09:35 ago) – Posting: # 1241
Views: 8,613

Dear HS

I didnt express my point correctly,

the limits to accept the concentration values in the unknown samples are 0.8xLLOQ upto 1.15xULOQ not the cc limits to be so.

e.g if my cc range between 1-100 ng/ml, then why not to accept the concentration of 0.8 ng/ml in the unknown samples, thus we already accept the accuracy for the LLOQ in the cc graph for the 20%.

regards
Charl

Complete thread:

• Dilution integrity pb070681 2007-10-19 07:03 
  • Dilution integrity Ramesh 2007-10-19 07:29
    • Dilution integrity Helmut 2007-10-19 13:45
      • Dilution integrity Charl 2007-10-22 09:09
        • Extrapolation <LLOQ or >ULOQ Helmut 2007-10-22 12:46
          • Extrapolation <LLOQ or >ULOQCharl 2007-10-23 09:27
            • Extrapolation <LLOQ or >ULOQ Helmut 2007-10-23 19:09
  • Dilution integrity pb070681 2007-10-24 07:03
    • Dilution integrity Helmut 2007-10-26 01:32