Bioequivalence and Bioavailability Forum • Dilution integrity

Dilution integrity [Bioanalytics]

posted by Ramesh – India, 2007-10-19 09:29 (6827 d 23:07 ago) – Posting: # 1222
Views: 9,801

Dear pramod,

your calibration range is from 2 - 100 ng.
any value out of the validated is not considered. if value is below the LOQ it will be considered as BLQ (below limit of quantification) and if the value is above the ULQ it will be repeated as Dilution integrity sample, but diluting the sample appropriately (to bring the concentration within the validation range) and back calculate by applying dilution factor.

i hope this is helpful to you

with regards,
Ramesh.V

—
with regards,

Ramesh

Complete thread:

Dilution integrity pb070681 2007-10-19 07:03
- Dilution integrityRamesh 2007-10-19 07:29
  - Dilution integrity Helmut 2007-10-19 13:45
    - Dilution integrity Charl 2007-10-22 09:09
      - Extrapolation <LLOQ or >ULOQ Helmut 2007-10-22 12:46
        
        Extrapolation <LLOQ or >ULOQ Charl 2007-10-23 09:27
        
        Extrapolation <LLOQ or >ULOQ Helmut 2007-10-23 19:09
- Dilution integrity pb070681 2007-10-24 07:03
  - Dilution integrity Helmut 2007-10-26 01:32