Bioequivalence and Bioavailability Forum

outliers test for QC sample [Bioanalytics]

posted by mathews – 2007-10-11 09:58 (6837 d 08:20 ago) – Posting: # 1172
Views: 11,661

Dear All,

How we can find the outliers in QC samples?

which test is best for finding the outliers? grubbs test or Dixons test?...why?...

Is there any other outlier tests?

usually in Bioanalytical application there are 6 QC in each set.

some literature says Grubbs test is not applicable if the sample size is less than or equal to 6. but in some papers they mentioned grubbs test is applicable from 3 to 100 sample?...which one is true?...

before applying Grubbs test, is it necessary to test whether the samples are normally distributed?

thanks and regards

mathews

Complete thread:

• outliers test for QC samplemathews 2007-10-11 07:58 
  • outliers test - but not for QCs! Helmut 2007-10-11 15:31
    • Outlier test - but not for QC's yuvrajkatkar 2010-01-19 08:49
      • Outlier test - but not for QC's H_Rotter 2010-01-19 12:55
      • Outlier tests: forget it! Helmut 2010-01-19 17:36
        • Outlier tests: forget it! Ohlbe 2010-01-19 19:00
          • Outlier tests: forget it! Helmut 2010-01-19 19:16
            • Outlier tests: forget it! Ohlbe 2010-01-19 21:00
              • QCs vs. calibrators Helmut 2010-01-19 21:49
                • QCs vs. calibrators Ohlbe 2010-01-20 19:01
                  • QCs vs. calibrators Helmut 2010-01-20 19:26
                    • QCs vs. calibrators Ohlbe 2010-01-20 19:52
              • Two thirds of QCs H_Rotter 2010-01-20 16:21
                • Two thirds of QCs Ohlbe 2010-01-20 18:49
              • Outlier tests: forget it!....what if.... moblak 2010-01-25 10:04
                • Outlier tests: forget it!....what if.... Ohlbe 2010-01-25 23:19