Freeze-thaw studies [Bioanalytics]

posted by Helmut Homepage – Vienna, Austria, 2013-09-04 16:43 (4288 d 02:08 ago) – Posting: # 11435
Views: 4,471

Hi Martin,

❝ Nope, no "true" initial concentration available (just 3 replicates prior first freezing step).


OK, expected that.

❝ I thought on linear regression and test the slope to be different for zero. However, I do not like this approach for obvious reasons ;-).


Yes, doesn’t make sense.

❝ Another approach may be to calculate the 95% CI for the mean at step 0 (kind of plausibility interval) and check if CI for the model-predictions is within that interval.

❝ What do you think?


Much better. See also the Hsin-ya’s and Yung-jin’s stab for R.

Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

UA Flag
Activity
 Admin contact
23,424 posts in 4,927 threads, 1,674 registered users;
22 visitors (0 registered, 22 guests [including 7 identified bots]).
Forum time: 18:51 CEST (Europe/Vienna)

Everything is trivial, if you know the answer.    Thomas Jaki

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5