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RegisterAnalyte measured to Lymecycline bioequivalence study [Bioanalytics]
Dear Mauricio,
The active ingredient lymecycline is a tetracycline antibiotic which is more readily absorbed from the gastro-intestinal tract than tetracycline, with a peak serum concentration of approximately 2mg/L after 3 hours following a 300 mg dose. It is a half synthetic combination of water soluble tetracyclin, the amino acid lysin and formaldehyd. After oral application this combination is hydrolised within the GI tract to tetracyclin, lysin and formaldehyd and therefore not available as lymecycline in the systemic circulation. In other words lymecycline is a pro-drug of tetracycline.
Kind regards
Dan
The active ingredient lymecycline is a tetracycline antibiotic which is more readily absorbed from the gastro-intestinal tract than tetracycline, with a peak serum concentration of approximately 2mg/L after 3 hours following a 300 mg dose. It is a half synthetic combination of water soluble tetracyclin, the amino acid lysin and formaldehyd. After oral application this combination is hydrolised within the GI tract to tetracyclin, lysin and formaldehyd and therefore not available as lymecycline in the systemic circulation. In other words lymecycline is a pro-drug of tetracycline.
Kind regards
Dan
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Kind regards and have a nice day
Dr_Dan
Kind regards and have a nice day
Dr_Dan
Complete thread:
- Analyte measured to Lymecycline bioequivalence study Mauricio Sampaio 2013-09-02 15:50
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Analyte measured to Lymecycline bioequivalence studyDr_Dan 2013-09-02 20:53
- Analyte measured to Lymecycline bioequivalence study Mauricio Sampaio 2013-09-03 19:58
- Analyte measured to Lymecycline bioequivalence study manojskr 2013-09-04 15:06
- Analyte measured to Lymecycline bioequivalence study Dr_Dan 2013-09-04 20:05
- Analyte measured to Lymecycline bioequivalence study manojskr 2013-09-05 05:54
- Analyte measured to Lymecycline bioequivalence study Dr_Dan 2013-09-04 20:05
- Analyte measured to Lymecycline bioequivalence studyDr_Dan 2013-09-02 20:53
Ing. Helmut Schütz