Bioequivalence and Bioavailability Forum

Dear Ohlbe!

❝ [...] The definitions given in the annex are rather outdated:

❝ Specific test procedure: ... quantitatively ...

❝ Selective test procedure: ... qualitatively ...

If if haven't forgotten everything from my chemistry studies there's a rank order, namely:
quantitative > qualitative
Therefore the EU document implies also specific > selective
which at least is in accordance with the IUPAC:
'Specific is considered to be the ultimate of selective.'

❝ By the way HS: unless I missed it this old EU guideline, still in force,

❝ is missing from your list of guidance documents. But I must admit it is

❝ really outdated (July 1990, if I'm not mistaken ?).

No, you are right, I added it to the collection (since it's referred at the 'Biologicals Guidelines' page, updated yesterday).
If it's from 1990 (where did you get the date from?) it does not beat the current record holder Pharmacokinetic Studies in Man from October 1988...

P.S.: Just realised that this is post no. 1000...