Use of Naltrexone prior to Naloxone dosing [Design Issues]

posted by Ionsource – Pakistan, 2013-01-10 07:15 (4913 d 23:03 ago) – Posting: # 9809
Views: 3,960

Hi John,

In fact my initial question was not that clearly written. Your answer is satisfactory. Since we are only using Naloxone and on drug free volunteers, we don't need to administer Naltrexone since both are receptor antagonists.

I had read the studies which were on Buprenorphine/Naloxone where investigators used Naltrexone since Buprenorphine being partial agonist can induce withdrawal symptoms. But it's not needed here. Have I got it right?

Regards

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