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RegisterUse of Naltrexone prior to Naloxone dosing [Design Issues]
Hi John,
In fact my initial question was not that clearly written. Your answer is satisfactory. Since we are only using Naloxone and on drug free volunteers, we don't need to administer Naltrexone since both are receptor antagonists.
I had read the studies which were on Buprenorphine/Naloxone where investigators used Naltrexone since Buprenorphine being partial agonist can induce withdrawal symptoms. But it's not needed here. Have I got it right?
Regards
In fact my initial question was not that clearly written. Your answer is satisfactory. Since we are only using Naloxone and on drug free volunteers, we don't need to administer Naltrexone since both are receptor antagonists.
I had read the studies which were on Buprenorphine/Naloxone where investigators used Naltrexone since Buprenorphine being partial agonist can induce withdrawal symptoms. But it's not needed here. Have I got it right?
Regards
Complete thread:
- Use of Naltrexone prior to Naloxone dosing Ionsource 2012-12-26 19:50
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Use of Naltrexone prior to Naloxone dosing jag009 2013-01-02 18:12
- Use of Naltrexone prior to Naloxone dosing Ionsource 2013-01-04 07:56
- Use of Naltrexone prior to Naloxone dosing jag009 2013-01-09 15:41
- Use of Naltrexone prior to Naloxone dosingIonsource 2013-01-10 06:15
- Use of Naltrexone prior to Naloxone dosing jag009 2013-01-10 16:41
- Use of Naltrexone prior to Naloxone dosingIonsource 2013-01-10 06:15
- Use of Naltrexone prior to Naloxone dosing jag009 2013-01-09 15:41
- Use of Naltrexone prior to Naloxone dosing Ionsource 2013-01-04 07:56
- Use of Naltrexone prior to Naloxone dosing jag009 2013-01-02 18:12
Ing. Helmut Schütz