Preferred study design for RSABE [Design Issues]

posted by jag009  – NJ, 2013-01-04 16:38 (4914 d 23:21 ago) – Posting: # 9785
Views: 3,223

Hi Prasad,

Check papers from Dr. Laszlo Endrenyi.

4-way fully rep design advantage? 1) further reduction in study sample size, 2) obtain information about the intrasubject variability of the test formulation.

Disadvantages? Longer to run and potential dropouts. Most are happy with 3-way rep.

John

Complete thread:

UA Flag
Activity
 Admin contact
23,655 posts in 4,993 threads, 1,570 registered users;
154 visitors (0 registered, 154 guests [including 36 identified bots]).
Forum time: 16:59 CEST (Europe/Vienna)

I have finally come to the konklusion
that a good reliable set ov bowels
iz worth more to a man
than enny quantity of brains.    Josh Billings

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5