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RegisterEnantiomer measurement for metabolite [Design Issues]
Dear Dr Gunasekaran,
Thanks for your reply,
Guidelines stating the below points, however the drug behaviour is as mentioned below,
(1) the enantiomers exhibit different pharmacokinetics - No
(2) the enantiomers exhibit pronounced difference in pharmacodynamics - Not sure, no data available
(3) the exposure (AUC) ratio of enantiomers is modified by a difference in the rate of absorption - Not sure, no data available
Thanks,
MSMN
Thanks for your reply,
Guidelines stating the below points, however the drug behaviour is as mentioned below,
(1) the enantiomers exhibit different pharmacokinetics - No
(2) the enantiomers exhibit pronounced difference in pharmacodynamics - Not sure, no data available
(3) the exposure (AUC) ratio of enantiomers is modified by a difference in the rate of absorption - Not sure, no data available
Thanks,
MSMN
—
Sundar. M
Sundar. M
Complete thread:
- Enantiomer measurement for metabolite msmnainar 2012-12-20 08:36
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Enantiomer measurement for metabolite drgunasakaran1 2012-12-22 12:28
- Enantiomer measurement for metabolitemsmnainar 2012-12-24 06:40
- Enantiomer measurement for metabolite Helmut 2012-12-24 14:29
- Enantiomer measurement for metabolitemsmnainar 2012-12-24 06:40
- Enantiomer measurement for metabolite drgunasakaran1 2012-12-22 12:28
Ing. Helmut Schütz