Log in
RegisterEnantiomer measurement for metabolite [Design Issues]
Hello all
I need clarification regarding the measurement of metabolite for those drug having racemic activity.
Both parent and its metabolites exhibit linear kinetics and its linear in pharmacokinetics, as per product label.
However, both parent and its metabolites exposure are different, as per literatures.
The study is for TGA submission.
Thanks and regards
MSMN
I need clarification regarding the measurement of metabolite for those drug having racemic activity.
Both parent and its metabolites exhibit linear kinetics and its linear in pharmacokinetics, as per product label.
However, both parent and its metabolites exposure are different, as per literatures.
The study is for TGA submission.
Thanks and regards
MSMN
—
Sundar. M
Sundar. M
Complete thread:
- Enantiomer measurement for metabolitemsmnainar 2012-12-20 08:36
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Enantiomer measurement for metabolite drgunasakaran1 2012-12-22 12:28
- Enantiomer measurement for metabolite msmnainar 2012-12-24 06:40
- Enantiomer measurement for metabolite Helmut 2012-12-24 14:29
- Enantiomer measurement for metabolite msmnainar 2012-12-24 06:40
- Enantiomer measurement for metabolite drgunasakaran1 2012-12-22 12:28
Ing. Helmut Schütz