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RegisterExclusion based on Minimum Non Zero Concentrations [Design Issues]
❝ Check the literature of the drug, if the range of Tmax of your drug is very high and make sure that you didn't captured the sampling time points based on the Median Tmax rather than the Range.
Sampling time points were optimised based on all available literature to capture Cmax
❝ If the drug has rapid distribution phase simiar to Risedronate, you may get profile like this.
Rapid distribution is not reported. In other subjects such behaviour is not observed
If you have any other idea to tackle such situation please let me know ....
Complete thread:
- Exclusion based on Minimum Non Zero Concentrations hiren379 2012-12-11 05:31
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Exclusion based on Minimum Non Zero Concentrations drgunasakaran1 2012-12-11 05:53
- Exclusion based on Minimum Non Zero Concentrationshiren379 2012-12-11 06:03
- Exclusion based on Minimum Non Zero Concentrations drgunasakaran1 2012-12-11 09:02
- Exclusion based on Minimum Non Zero Concentrationshiren379 2012-12-11 06:03
- Exclusion based on Minimum Non Zero Concentrations drgunasakaran1 2012-12-11 05:53
Ing. Helmut Schütz