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RegisterMultiplicity: Mixed feelings [Design Issues]
dear all!
you have several strategies to accound for multiplicity (e.g. Bonferroni, fixed sequence testing procedure with a-priori ordered hypothesis, …). However, I would suggest to have a close look at the intersection-union princple:
If all calculated two-sided 90% CI are within the acceptance range – the type I error is controlled strongly. Please refer to Wellek (2010; page 219) for more detail.
hope this helps
Martin
PS.: see also this post IUT principle
you have several strategies to accound for multiplicity (e.g. Bonferroni, fixed sequence testing procedure with a-priori ordered hypothesis, …). However, I would suggest to have a close look at the intersection-union princple:
If all calculated two-sided 90% CI are within the acceptance range – the type I error is controlled strongly. Please refer to Wellek (2010; page 219) for more detail.
hope this helps
Martin
PS.: see also this post IUT principle
Complete thread:
- Two Tests with Same Reference Noha Abdeljawad 2012-11-27 08:18
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Crossover designs with more than 2 treatments d_labes 2012-11-27 09:51
- Crossover designs with more than 2 treatments Noha Abdeljawad 2012-11-29 07:43
- Sounds wrong to me ElMaestro 2012-11-27 12:10
- Sounds wrong to me Dr_Dan 2012-11-27 14:32
- Sounds wrong to me Noha Abdeljawad 2012-11-29 07:52
- Two Tests with Same Reference jag009 2012-11-28 21:26
- FDA & multiplicity Helmut 2012-11-30 14:04
- FDA & multiplicity jag009 2012-11-30 15:16
- FDA & multiplicity Helmut 2012-11-30 16:12
- FDA & multiplicity jag009 2012-11-30 22:47
- FDA & multiplicity Helmut 2012-12-01 02:00
- FDA & multiplicity jag009 2012-12-03 21:53
- FDA & multiplicity Helmut 2012-12-01 02:00
- FDA & multiplicity jag009 2012-11-30 22:47
- FDA & multiplicity Helmut 2012-11-30 16:12
- Multiplicity: Mixed feelings ElMaestro 2012-11-30 15:24
- Multiplicity: Mixed feelings Helmut 2012-11-30 15:52
- Multiplicity: Mixed feelingsmartin 2012-12-03 09:24
- Multiplicity: Mixed feelings kumarnaidu 2013-12-12 11:03
- More infos, please Helmut 2013-12-12 15:27
- Multiplicity: Mixed feelings Helmut 2012-11-30 15:52
- FDA & multiplicity jag009 2012-11-30 15:16
- Two Tests with Same Reference Noha Abdeljawad 2012-12-03 08:29
- Two Tests with Same Reference jag009 2012-12-03 15:35
- X-way d_labes 2012-12-04 09:25
- design kvgreddy06 2013-12-19 15:32
- design kvgreddy06 2013-12-30 16:48
- design intuitivepharma 2013-12-31 06:44
- design kumarnaidu 2013-12-31 08:24
- Problematic design Helmut 2013-12-31 15:02
- Problematic design kvgreddy06 2014-01-03 14:46
- Problematic design kumarnaidu 2014-12-24 12:56
- Problematic design Helmut 2014-12-24 16:10
- Problematic design kumarnaidu 2014-12-26 05:38
- Two fully replicated designs? Helmut 2014-12-27 15:52
- Problematic design kumarnaidu 2014-12-26 05:38
- Problematic design Helmut 2014-12-24 16:10
- Problematic design Helmut 2013-12-31 15:02
- design kumarnaidu 2013-12-31 08:24
- design intuitivepharma 2013-12-31 06:44
- design kvgreddy06 2013-12-30 16:48
- design kvgreddy06 2013-12-19 15:32
- X-way d_labes 2012-12-04 09:25
- Two Tests with Same Reference jag009 2012-12-03 15:35
- FDA & multiplicity Helmut 2012-11-30 14:04
- Crossover designs with more than 2 treatments d_labes 2012-11-27 09:51
Ing. Helmut Schütz