OROS residence time [Design Issues]

posted by jag009  – NJ, 2012-09-18 19:11 (5028 d 10:35 ago) – Posting: # 9236
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Hi Helmut,

❝ “Earlier” is a comparative degree; so earlier compared to?


With reference to GI Transit time? Or do a fecal inspection if subject has a bowel movement in less than 24 hours? Dissolution for OROS tablets usually achieve 90% release by 12-16 hours?

John

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