Update [Design Issues]

posted by Helmut Homepage – Vienna, Austria, 2007-07-09 15:58 (6929 d 02:35 ago) – Posting: # 873
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Different volumes (between 100 ml and 250 ml) are recommended in some national guidelines.
An overwiew of updated guidelines is given below:

Japan
water between 100 and 200 ml (normally 150 ml)
http://www.nihs.go.jp/drug/be-guide/GL061124_ganryo.pdf (2006, in Japanese)

Argentina
200-250 ml water
http://www.anmat.gov.ar/normativa/Normativa/Medicamentos/Disposicion_ANMAT_1746-2007.pdf (2007, in Spanish)

South Africa
e.g. 200 ml fluid
http://www.mccza.com/documents/2.06%20Biostudies%20Jun07%20v2.zip (2007)

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