Bioequivalence and Bioavailability Forum

Common variance! [Design Issues]

posted by jag009  – NJ, 2012-06-11 22:03 (5130 d 16:15 ago) – Posting: # 8687
Views: 11,265

Hi Helmut

❝ Everybody wants to kill two birds with one stone. What you essentially would need is a full adaptive design (adjusting for observed PEs and CVs). This is one of our member’s specialty. Acceptance? No idea.

I thought about adaptive design as well but then timing would become an issue since bioanalytical would be involved during the process? The stupid thing is we want to test all and hit the spot with one (hopefully). It is a resource (outsourcing) vs time issue.

I am the planner designer executioner (or whatever, not the one with the sickle), higher up gives the call (timeframe wise)

Complete thread:

• Curiosity: Running BE studies with more than 2 arms jag009 2012-06-11 15:01 
  • Common variance! Helmut 2012-06-11 16:23
    • Common variance! jag009 2012-06-11 17:25
      • Common variance! Helmut 2012-06-11 17:35
        • Common variance!jag009 2012-06-11 20:03
          • Common variance! ElMaestro 2012-06-11 20:34
            • Common variance! Helmut 2012-06-12 01:03
              • Common variance! ElMaestro 2012-06-12 13:22
    • Common variance! jag009 2012-06-12 19:56
      • What if I run a study with 2 references? jag009 2012-06-12 20:00
      • Common variance! Helmut 2012-06-12 20:39
        • Two References d_labes 2012-06-13 09:11
          • Two References jag009 2012-09-10 22:48
            • Two treatments only d_labes 2012-09-11 08:20
    • Common variance! jag009 2012-06-13 16:08