Highly variable long half life drug parallel add on design? [Design Issues]

posted by Dr_Dan  – Germany, 2011-10-11 12:05 (5374 d 19:29 ago) – Posting: # 7468
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Dear all
One question to Helmut:
Is it possible to conduct in case of a highly variable long half life drug a parallel group study with an add on design?
Rationale: widening of acceptance range not possible due to the fact that the replicate design is out of question but intention to be more on the safe side with the possibility to adapt sample size.
Kind regards
Dan

Kind regards and have a nice day
Dr_Dan

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