Bioequivalence and Bioavailability Forum • bioavailability study on rats

bioavailability study on rats [Design Issues]

posted by A-M-R – Egypt, 2011-03-10 15:06 (5586 d 08:14 ago) – Posting: # 6743
Views: 5,186

I will carrying out a comparative study between metformin on one side and on the other side (metformin and amoxycillin), the study will be carried out on rats to study the effect of amoxycillin on the pharmacokinetics of metformin. can you help me in finding the most suitable design for this study and if it is possible to take whole blood of the rat at each time interval (9 time points) especially the time interval will be for 8 hours and the project for statistical calculations in this case.
very thanks
Amr hussein

Complete thread:

bioavailability study on ratsA-M-R 2011-03-10 14:06
- bioavailability study on rats ElMaestro 2011-03-10 14:33
- bioavailability study on rats martin 2011-03-10 15:09
  - bioavailability study on rats A-M-R 2011-03-16 10:07
- Sampling volumes martin 2011-03-10 16:53
- Sampling volumes manan 2011-03-11 06:40