Bioequivalence and Bioavailability Forum • Time Points of Blood Collections

Time Points of Blood Collections [Design Issues]

posted by Helmut – Vienna, Austria, 2010-12-27 15:43 (5659 d 02:31 ago) – Posting: # 6344
Views: 5,101

Dear Phani!

❝ […] the points are 00:00, 00:30, 01:00, 01:50, 02:00, 02:50, 03:00, 03:50, 04:00... hrs

❝ Is this not haphazard sampling

No, only crazy, IMHO.
Time intervals in the absorption phase and around C_max should be evenly spaced and follow a geometric progression in the distribution/elimination phase.
What do we have here? 00:30, 00:30, 0:50, 00:10, 00:50, 00:10, 00:50, 00:10… Weird. Are you sure the [hh]:50 is not the result of a copypaste error and should read [hh]:30 instead?

Additionally to Manan’s and Vivek’s posts, have a look at this one as well.

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Complete thread:

Time Points of Blood Collections Phaneendra.K 2010-12-27 06:05
- Time Points of Blood Collections manan 2010-12-27 07:04
- Time Points of Blood Collections VRP 2010-12-27 07:09
- Time Points of Blood CollectionsHelmut 2010-12-27 14:43
  - Time Points of Blood Collections ElMaestro 2010-12-27 17:29
    - Time Points of Blood Collections Helmut 2010-12-27 17:47
    - Time Points of Blood Collections Phaneendra.K 2010-12-31 14:33
- Time Points of Blood Collections pravin17 2010-12-30 07:03
  - Time Points of Blood Collections Phaneendra.K 2010-12-31 14:31