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Registerselection of time points [Design Issues]
Dear Martin
Thank you for the guidance. But in this case Tmax of active (R)- enantiomer is 15-48 hr and that of inactive (S)- enantiomer is 2-5 hr. Should I consider the Tmax of both the (R) & (S) - enantiomers of Bicalutamide for deciding time points or only the active(R)- enantiomer which we are analyzing.
Also the Tmax range of 15-48 hr is quite wide. In this case how to decide the time points so as not to miss the real Cmax.
Please suggest.
Dr Muneesh Garg
Thank you for the guidance. But in this case Tmax of active (R)- enantiomer is 15-48 hr and that of inactive (S)- enantiomer is 2-5 hr. Should I consider the Tmax of both the (R) & (S) - enantiomers of Bicalutamide for deciding time points or only the active(R)- enantiomer which we are analyzing.
Also the Tmax range of 15-48 hr is quite wide. In this case how to decide the time points so as not to miss the real Cmax.
Please suggest.
Dr Muneesh Garg
Complete thread:
- time points and study design drmuneesh 2009-03-31 11:04
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- time points and study design MGR 2009-04-01 08:18
- time points and study design drmuneesh 2009-04-02 11:10
- selection of time points martin 2009-04-03 08:45
- time points and study design drmuneesh 2009-04-02 11:10
- time points and study design MGR 2009-04-01 08:18
Ing. Helmut Schütz