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RegisterInclusion Criteria in studies of postmenopausal females [Design Issues]
Dear Muneesh,
Are these normal ranges the published ones for that age? Notice, that normal ranges depend on the laboratory, which is analyzing the samples.
It dpends on the influence of the BMI on the endpoint.
@3: Again; it depends on your endpoint. If the concomitant mediccation is suggested to have a high impact, these patients are excluded often. If the impact is low, they may continue intake all over the study to have the same bias with all measurements. Alternatively the intake may be stopped (depending on the medication), but this has to be done as long before the study starts as possible.
The same as to point 3.
Regards,
JPL
❝ Normal range of -estradiol for postmenopausal
❝ females is 10.0-44.0 ng/ml and of FSH levels is 17.0-95.0 mIU/ml. Then
❝ what levels should we consider for -estradiol and FSH in studies
❝ of postmenopausal females.
Are these normal ranges the published ones for that age? Notice, that normal ranges depend on the laboratory, which is analyzing the samples.
❝ 2. What should be the range for BMI as it is difficult to get BMI between
❝ 18 and 25 in that age group.
It dpends on the influence of the BMI on the endpoint.
@3: Again; it depends on your endpoint. If the concomitant mediccation is suggested to have a high impact, these patients are excluded often. If the impact is low, they may continue intake all over the study to have the same bias with all measurements. Alternatively the intake may be stopped (depending on the medication), but this has to be done as long before the study starts as possible.
❝ 4. What about subjects having diabetes and taking medicines for the same.
The same as to point 3.
Regards,
JPL
Complete thread:
- Inclusion Criteria in studies of postmenopausal females drmuneesh 2009-02-05 12:48
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Inclusion Criteria in studies of postmenopausal femalesJPL 2009-02-05 15:12
- Inclusion Criteria in studies of postmenopausal females drmuneesh 2009-02-06 05:28
- Inclusion Criteria in studies of postmenopausal females Helmut 2009-02-06 12:28
- Inclusion Criteria in studies of postmenopausal females drmuneesh 2009-02-07 06:12
- To BMI or not to BMI, that's the question Helmut 2009-02-07 11:58
- To BMI or not to BMI, that's the question drmuneesh 2009-02-09 04:54
- To BMI or not to BMI, that's the question Helmut 2009-02-07 11:58
- Inclusion Criteria in studies of postmenopausal females drmuneesh 2009-02-07 06:12
- Interruption of background treatment ??? Ohlbe 2009-02-07 23:42
- Interruption of background treatment ??? drmuneesh 2009-02-09 04:50
- Inclusion Criteria in studies of postmenopausal females Helmut 2009-02-06 12:28
- Inclusion Criteria in studies of postmenopausal females drmuneesh 2009-02-06 05:28
- Inclusion Criteria in studies of postmenopausal femalesJPL 2009-02-05 15:12
Ing. Helmut Schütz