Bioequivalence and Bioavailability Forum • randomization

randomization [Design Issues]

posted by bala – Bangalore, India, 2009-01-21 14:10 (6362 d 10:41 ago) – Posting: # 3092
Views: 5,260

Dear Neethu...

This is the first time I m hearing this kind of study... In FDA and other guidelines I am not able to locate this kind of study, however I will give you one layout for this...

Totally 24 subjects


Sequences 

1. T R T

2. T T R

3. R T T

We can randomize 8 patients with sequences (1,2)
8 patients with sequences (1,3)
8 patients with sequences (2,3)

Where subjects who were assigned (1,2) will receive T R T T T R in the 6 periods...

Similarly the others...

Just check with your protocol whether its allowing this...

—
Cheers
Bala

Complete thread:

randomization neethu 2009-01-21 12:31
- randomization bala 2009-01-21 12:35
  - randomization neethu 2009-01-21 12:39
    - randomization bala 2009-01-21 12:42
      - randomization neethu 2009-01-21 12:44
        
        randomizationbala 2009-01-21 13:10
        
        randomization Helmut 2009-01-21 13:17
        
        randomization Helmut 2009-01-21 13:14
        
        randomization bala 2009-01-21 13:20
        
        randomization Helmut 2009-01-21 13:27
        
        randomization bala 2009-01-21 13:30
        
        randomization neethu 2009-01-22 05:10
        
        randomization bala 2009-01-22 07:04
        
        randomization Helmut 2009-01-23 01:21