Bioequivalence and Bioavailability Forum • S × F interaction

S × F interaction [Design Issues]

posted by Brus – Spain, 2023-06-06 13:02 (1107 d 07:51 ago) – Posting: # 23577
Views: 5,227

Dear Helmut,

I don't understand the subject-by-formulation effect, can it only be studied in full replicated designs? If the subject-by-formulation effect is the change between test and reference difference means from one subject to another, in a 2x2 design it should be possible to study it. Right?

And in that case it could also be measured in partial replicate. Right?

Maybe I'm confused or don't understand something.

Thank you so much

Best regards,

Complete thread:

Switchability with replicate design studies Achievwin 2022-05-20 04:44
- Switchability = IBE Helmut 2022-05-20 09:17
  - Switchability = IBE Achievwin 2022-05-20 14:19
    - S × F interaction Helmut 2022-05-20 15:33
      - S × F interaction Achievwin 2022-05-20 23:32
      - S × F interactionBrus 2023-06-06 11:02
        
        S × F interaction Helmut 2023-06-07 10:34
        
        S × F interaction Achievwin 2023-06-08 10:21