Bioequivalence and Bioavailability Forum • Washout based on mean ± SD of t½

Washout based on mean ± SD of t½ [Design Issues]

posted by Imph – 2023-05-27 01:31 (767 d 15:30 ago) – Posting: # 23571
Views: 3,601

❝ ❝ Is it right to do "7 x t1/2 mean" without taking into consideration the SD?

❝

Hi,

I am here again about the way of taking into account the standard deviation described on page 64 of the presentation. Using the t1/2 +/-SD given in the SmPC, what sample size can be used? is it correct to use the sample size I plan to use in my study?

Thank you very much.

Complete thread:

Washout based on mean ± SD of t½ Imph 2022-09-25 13:52
- Washout based on mean ± SD of t½ Helmut 2022-09-25 16:08
  - Washout based on mean ± SD of t½ Imph 2022-09-26 15:24
    - Washout based on mean ± SD of t½ Shuanghe 2022-09-26 17:34
    - Washout based on mean ± SD of t½ Helmut 2022-09-26 17:35
    - If you have data… Helmut 2022-09-27 11:52
      - If you have data… Imph 2022-10-25 09:21
  - Washout based on mean ± SD of t½Imph 2023-05-26 23:31
    - Washout based on mean ± SD of t½ Helmut 2023-05-27 06:52
      - Washout based on mean ± SD of t½ Imph 2023-05-27 08:36