Bioequivalence and Bioavailability Forum • Definition of Full Replicate

Definition of Full Replicate [Design Issues]

posted by Sereng – USA, 2023-03-14 00:38 (1192 d 21:00 ago) – Posting: # 23496
Views: 9,601

Hi Mahmoud, thank you for your response. I think you may have misunderstood my question. I have always understood a "full replicate" design to be one where each treatment condition is repeated twice. Therefore, if the Test was being compared with Reference in the fasted state, a full replicate would involve giving both the Test and Reference on two occasions. Is this correct? Furthermore, calling a four-way fed fasted crossover study (Test Fed & Fasted, and Ref Fed & fasted), each given once a Full Replicate study would be wrong. is this correct?

—
Biostatistically Challenged CEO

Complete thread:

Definition of Full Replicate Sereng 2023-03-13 17:08
- Definition of Full Replicate Mahmoud 2023-03-13 20:27
  - Definition of Full ReplicateSereng 2023-03-13 23:38
    - Definition of Full Replicate Mahmoud 2023-03-14 08:44
      - Definition of Full Replicate Achievwin 2023-03-27 19:08
        
        Full Replicate with 3 periods mittyri 2023-03-27 22:16
        
        Full Replicate with 3 periods Achievwin 2023-03-28 03:06
        Full Replicate with 3 periods Helmut 2023-03-28 09:03
- Definition of Full Replicate Brus 2023-03-14 10:10
- Replicate Design ≠ Higher-Order Crossover Helmut 2023-03-14 10:37
  - Thank You! Sereng 2023-03-14 20:08
  - Replicate Design ≠ Higher-Order Crossover Relaxation 2023-03-20 08:56
    - imbalance in Latin Square mittyri 2023-03-27 23:01
    - Balance for all effects Helmut 2023-04-21 10:01