long acting Injection [Design Issues]

posted by jag009  – NJ, 2020-04-21 23:06 (2258 d 01:41 ago) – Posting: # 21342
Views: 3,489

Hi,

❝ But if it is mentioned in monograph that half-life is 17 days following single dose and 46 days after multiple dose, then which half-life we should consider while designing multiple dose study? In the same monograph, it is also stated that steady state is achieved after 4th dose on injection.


Have you found out why the increase in half-life?

J

Complete thread:

UA Flag
Activity
 Admin contact
23,655 posts in 4,993 threads, 1,572 registered users;
303 visitors (0 registered, 303 guests [including 20 identified bots]).
Forum time: 00:47 CEST (Europe/Vienna)

Don’t compromise yourself.
You are all you’ve got.    Janis Joplin

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5