Bioequivalence and Bioavailability Forum • Replicate designs: Pros & Cons

Replicate designs: Pros & Cons [Design Issues]

posted by Balaji – India, 2017-03-04 12:19 (3403 d 19:35 ago) – Posting: # 17131
Views: 13,955

Hello Helmut,

Thanks for your clarification on the semi replicate and replicate designs.
However could you please elaborate on the below . .

❝ In the worst case the study is done and the optimizer fails to converge (independent from the software)

- What do you meanly optimiser fails to converge ? When does this happen ?

Edit: Standard quotes restored; see also this post #8. [Helmut]

Complete thread:

Replicate designs VSL 2017-01-31 06:47
- Replicate designs: Pros & Cons Helmut 2017-01-31 12:42
  - Replicate designs: Pros & Cons VSL 2017-01-31 14:03
  - Replicate designs: Pros & ConsBalaji 2017-03-04 11:19
    - Partial replicate design & ABE for the FDA Helmut 2017-03-06 11:40
      - Partial replicate design & ABE for the FDA nobody 2017-03-06 13:47
        
        Partial replicate design & ABE for the FDA Helmut 2017-03-06 14:00
        
        Partial replicate design & ABE for the FDA nobody 2017-03-06 14:18
        
        Partial replicate design & ABE for the FDA Helmut 2017-03-06 17:49

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