PPI Washout [Design Issues]

posted by jag009  – NJ, 2016-05-16 00:19 (3698 d 11:12 ago) – Posting: # 16311
Views: 5,336

❝ Dear Jay,

❝

❝ ❝ The halflife of Proton pump inhibitors is around 2 hrs, so 10 half life sums up to 20 hrs. So for BE Study considering the washout as 1-2 days would be acceptable?

❝

❝ This is elimination half life we are talking about not the half life of drug action. ;-)


You are using mean? Better look at the SD and ranges.

John

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