Bioequivalence and Bioavailability Forum • Bio Availability or Bio Equivalence study

Bio Availability or Bio Equivalence study [Design Issues]

posted by jag009 – NJ, 2016-05-10 01:09 (3703 d 21:45 ago) – Posting: # 16285
Views: 9,917

Hi Ohlbe

❝ Do you think an extended release formulation can be bioequivalent to an immediate release fomulation ?

It is possible if he is talking about a ER q.d. vs IR b.i.d (or t.i.d, or q.i.d.) formulation under the same total daily dose where in some cases one might want to demonstrate bioquivalence between the two products. Example, Ultram ER is bioequivalent to Tramadol IR (given as qid)....

John

Complete thread:

Reg-Bio Availability or Bio Equivalence study pravin17 2016-05-03 08:07
- Bio Availability or Bio Equivalence study Ohlbe 2016-05-03 10:25
  - Bio Availability or Bio Equivalence studyjag009 2016-05-09 23:09
    - Different rates = BE if intentional (FDA def.) Helmut 2016-05-10 16:08
      - Different rates = BE if intentional (FDA def.) Ohlbe 2016-05-10 22:03
- Bio Availability or Bio Equivalence study nobody 2016-05-03 10:41
- Bioequivalence study? Helmut 2016-05-03 11:55
  - Bioequivalence study? nobody 2016-05-03 14:07
  - Bioequivalence study d_labes 2016-05-03 15:50
    - Bioequivalence study Helmut 2016-05-03 17:44
      - Investigation of ... d_labes 2016-05-04 08:43