Bioequivalence and Bioavailability Forum

cortisol suppression as clinical end­point [Design Issues]

posted by nobody – 2015-11-12 17:06 (3875 d 06:11 ago) – Posting: # 15633
Views: 13,234

Scientific rational for your borders chosen? What do you evaluate? AUC?

What if cortisol fails, but your other BE passes?

I would invest some days and go to the basics before you shoot yourself in the knee with a protocol full of nonsense (as you might learn in the end).

Complete thread:

• cortisol suppression as clinical endpoint lizhao 2014-09-10 23:21 
  • cortisol suppression as clinical endpoint ElMaestro 2014-09-10 23:42
  • cortisol suppression as clinical endpoint nobody 2014-09-11 08:45
    • cortisol suppression as clinical endpoint lizhao 2014-09-11 23:00
      • cortisol suppression as clinical endpoint nobody 2014-09-12 13:59
        • cortisol suppression as clinical endpoint ElMaestro 2014-09-12 14:56
          • cortisol suppression as clinical endpoint nobody 2014-09-12 16:00
            • cortisol suppression as clinical end­point lizhao 2015-11-12 02:15
              • cortisol suppression as clinical end­point nobody 2015-11-12 08:27
                • cortisol suppression as clinical end­­point lizhao 2015-11-12 11:07
                  • cortisol suppression as clinical end­pointnobody 2015-11-12 16:06
                  • cortisol suppression as clinical end­point ElMaestro 2015-11-13 18:39
                    • cortisol suppression as clinical end­point lizhao 2015-11-13 20:56
                    • cortisol suppression as clinical end­point lizhao 2015-12-02 23:00