Bioequivalence and Bioavailability Forum

Hi HS,

A small doubt regarding the example you had given,

❝ Example:

❝ 6x3 design, sample size 30, clinical capacity 18 beds.

❝ 1^st group 18 subjects (3 blocks of 6 sequences), 2^nd group 12 subjects (2 blocks of 2 sequences).

In this type of study (means conducting in two groups) Is it compulsory to generate a randomization schedule seperately for each group? or can we generate the randomization schedule at one time containing all the 30 subjects? Please clarify this. As iam in a confusion that two we had done a study with two groups but the randomization had given at once (means in one schedule at the time of group I check-in)? Iam very grateful if you provide me an answer. Thanks in advance.