Rabeprazole not a HVD [Design Issues]

posted by Helmut Homepage – Vienna, Austria, 2007-11-23 18:27 (6792 d 09:01 ago) – Posting: # 1327
Views: 12,962

Dear Nirali!

❝ Is Rabeprazole Highly Variable Drug (HVD)?

❝ Inter-Subject variability is more than 50%?


Most likely not.

See these two references (both on single dose of 20mg):
  1. Mondal U, Ganesan M, Pal TK, Jayakumar M, Chattaraj TK, Roy K, Banerjee SN
    Bioequivalence study of rabeprazole sodium on healthy human volunteers
    J Indian Med Assoc 102(1): 26-30 (2004)
  2. Chen J, Jiang WM, Gao XL, Jiang X, Zhang QZ, Zheng ZH
    Bioequivalence evaluation of two rabeprazole enteric coated formulations in healthy Chinese volunteers
    Eur J Drug Metab Pharmacokinet 29(2): 103-106 (2004)

Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

UA Flag
Activity
 Admin contact
23,655 posts in 4,993 threads, 1,570 registered users;
358 visitors (0 registered, 358 guests [including 32 identified bots]).
Forum time: 04:28 CEST (Europe/Vienna)

Most scientists today are devoid of ideas, full of fear, intent on
producing some paltry result so that they can add to the flood
of inane papers that now constitutes “scientific progress”
in many areas.    Paul Feyerabend

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5