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RegisterFixed dose combinations [Design Issues]
Dear All,
If we want to demonstrate BE for an FDC in which one drug is highly variable (CV>30%)and other one with CV ~20% then in this case should we opt scaled approach(replicate design) or 2x2 crosover design?
If we want to demonstrate BE for an FDC in which one drug is highly variable (CV>30%)and other one with CV ~20% then in this case should we opt scaled approach(replicate design) or 2x2 crosover design?
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Kumar Naidu
Kumar Naidu
Complete thread:
- BE of product with two drugs Ken Peh 2013-02-25 13:58
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Fixed dose combinations Helmut 2013-02-26 16:12
- Fixed dose combinations Ken Peh 2013-02-28 15:39
- Fixed dose combinationskumarnaidu 2014-03-19 10:43
- Fixed dose combinations Ken Peh 2013-02-28 15:39
- Fixed dose combinations Helmut 2013-02-26 16:12
Ing. Helmut Schütz